NASH Target Development Services for Inflammation

Non-alcoholic steatohepatitis (NASH) is a progressive liver disease strongly associated with inflammation and oxidative stress. Inflammation and oxidative stress in NASH play a critical role in the pathogenesis and progression of liver damage, often leading to fibrosis and cirrhosis. Research has shown that elevated levels of oxidative stress in liver cells contribute to the accumulation of reactive oxygen species (ROS), which in turn triggers inflammatory responses. This vicious cycle exacerbates liver injury and accelerates disease progression in individuals with NASH. Understanding the underlying mechanisms of inflammation and oxidative stress in NASH is crucial for developing targeted therapeutic strategies aimed at halting or reversing the disease process.